Summary for publication

RHAPSODY produces annual publishable reports which describe the project achievements. They are public and and the latest can be downloaded by clicking on the link below.

Project Flyer

The RHAPSODY project flyer describes the project at a glance. It is mainly intended as a printed product but its electronic version is available for download.

Scientific publications

Publications in peer-reviewed journals, conference proceedings, book chapters and books.
The Expression of Aldolase B in Islets Is Negatively Associated With Insulin Secretion in Humans.
The Journal of Clinical Endocrinology & Metabolism 103, 4373-4383 (2018). doi:10.1210/jc.2018-00791
Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes.
Nucleic Acids Research 46, 10302-10318 (2018). doi:10.1093/nar/gky839
Prediction of Glucose Tolerance without an Oral Glucose Tolerance Test.
Frontiers in Endocrinology 9, (2018). doi:10.3389/fendo.2018.00082
Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables.
The Lancet Diabetes & Endocrinology 6, 361-369 (2018). doi:10.1016/S2213-8587(18)30051-2
Modeling human pancreatic beta cell dedifferentiation.
Molecular Metabolism 10, 74-86 (2018). doi:10.1016/j.molmet.2018.02.002
Manipulation and Measurement of AMPK Activity in Pancreatic Islets.
in AMPK (Neumann, D. & Viollet, B.eds. ) 1732, 413-431 (Springer New York, 2018).
MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells.
Diabetes 67, 461-472 (2018). doi:10.2337/db17-0595
HbA1c is associated with altered expression in blood of cell cycle- and immune response-related genes.
Diabetologia 61, 138-146 (2018). doi:10.1007/s00125-017-4467-0
Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells.
Molecular Metabolism 6, 1024-1039 (2017). doi:10.1016/j.molmet.2017.06.001
Lifestyle and precision diabetes medicine: will genomics help optimise the prediction, prevention and treatment of type 2 diabetes through lifestyle therapy?.
Diabetologia 60, 784-792 (2017). doi:10.1007/s00125-017-4207-5
Computer simulation models of pre-diabetes populations: a systematic review protocol.
BMJ Open 7, e014954 (2017). doi:10.1136/bmjopen-2016-014954
Painting a new picture of personalised medicine for diabetes.
Diabetologia 60, 793-799 (2017). doi:10.1007/s00125-017-4210-x
Lifestyle precision medicine: the next generation in type 2 diabetes prevention?.
BMC Medicine 15, (2017). doi:10.1186/s12916-017-0938-x
Local and regional control of calcium dynamics in the pancreatic islet: RUTTER et al .
Diabetes, Obesity and Metabolism 19, 30-41 (2017). doi:10.1111/dom.12990

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This project receives funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 115881. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA.

This work is supported by the Swiss State Secretariat for Education‚ Research and Innovation (SERI) under contract number 16.0097-2.

The opinions expressed and arguments employed herein do not necessarily reflect the official views of these funding bodies.